Ulgixal may be available in the countries listed below.
Pemirolast potassium salt (a derivative of Pemirolast) is reported as an ingredient of Ulgixal in the following countries:
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Generic Name: rifampin (rif AM pin)
Brand names: Rifadin, Rimactane, Rifadin IV
Rifampin is an antibiotic. Rifampin prevents bacteria from spreading in your body.
Rifampin is used to treat or prevent tuberculosis (TB).
Rifampin may also be used to eliminate a bacteria from your nose and throat that may cause meningitis or other infections, even if you do not have an infection. Rifampin prevents you from spreading this bacteria to other people, but the medication will not treat an infection caused by the bacteria.
Rifampin may also be used for other purposes not listed in this medication guide.
Before taking rifampin, tell your doctor if you are allergic to any drugs, or if you have liver disease or porphyria ( (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).
Do not wear contact lenses while you are taking rifampin. This medicine may discolor your tears, which could permanently stain soft contact lenses.
Before taking rifampin, tell your doctor if you are allergic to any drugs, or if you have:
liver disease; or
porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).
If you have any of these conditions, you may need a dose adjustment or special tests to safely take rifampin.
Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take extra medicine to make up a missed dose.
Overdose symptoms may include nausea, vomiting, itching, headache, weakness, fast or uneven heart rate, or feeling like you might pass out.
Do not wear contact lenses while you are taking rifampin. This medicine may discolor your tears, which could permanently stain soft contact lenses.
fever, chills, body aches, flu symptoms;
joint pain or swelling;
easy bruising or bleeding, weakness;
urinating less than usual or not at all; or
nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
tired feeling; or
red or orange colored urine, stools, tears, sweat, or saliva.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Tuberculosis -- Active:
The manufacturer recommends: 10 mg/kg (not to exceed 600 mg) orally or IV once a day
The American Thoracic Society (ATS), Centers for Disease Control and Prevention (CDC), and Infectious Diseases Society of America (IDSA) recommend:
Daily regimen: 10 mg/kg (up to 600 mg/day) orally or IV once a day
Intermittent regimen: 10 mg/kg (up to 600 mg/dose) orally or IV 2 or 3 times a week
A three-drug regimen consisting of isoniazid, rifampin, and pyrazinamide is recommended in the initial phase of short-course therapy which is usually continued for 2 months. Treatment should then be continued with isoniazid and rifampin for at least 4 months. Treatment duration should be extended if the patient's sputum or culture remains positive, if resistant organisms are present, or if the patient is HIV positive.
The Advisory Council for the Elimination of Tuberculosis, the ATS, and the CDC recommend adding streptomycin or ethambutol as a fourth drug in a regimen including isoniazid, pyrazinamide, and rifampin for initial treatment of tuberculosis unless the probability of isoniazid or rifampin resistance is very low. The need for a fourth drug should be reevaluated when susceptibility test results are known. If current community rates of isoniazid resistance are less than 4%, initial treatment with less than 4 drugs may be considered.
Usual Adult Dose for Tuberculosis -- Latent:
Patients with a positive tuberculin test without evidence of disease: 10 mg/kg (not to exceed 600 mg) orally or IV once a day for 4 months
While isoniazid monotherapy is usually sufficient for treatment with a positive tuberculin skin test and no signs of disease, rifampin may be used if isoniazid resistance is suspected or if isoniazid is not tolerated.
Usual Adult Dose for Meningococcal Meningitis Prophylaxis:
Treatment of asymptomatic carriers of Neisseria meningitidis to eliminate meningococci from the nasopharynx: 600 mg orally or IV twice a day for 2 days
Usual Adult Dose for Haemophilus influenzae Prophylaxis:
600 mg orally or IV once a day for 4 consecutive days
Usual Adult Dose for Endocarditis:
300 mg orally or IV every 8 hours for 6 weeks
Used concomitantly with nafcillin or vancomycin for the treatment of endocarditis in the presence of prosthetic material. Gentamicin is often added for the first 2 weeks of therapy.
Usual Adult Dose for Legionella Pneumonia:
600 mg orally or IV once a day for 14 days
May be added to erythromycin therapy
Usual Adult Dose for Nasal Carriage of Staphylococcus aureus:
600 mg orally or IV twice a day for 5 days for the treatment of chronic carriage of Staphylococcus aureus
Rifampin monotherapy or rifampin plus penicillin has been shown to eradicate staphylococci and Streptococcus pyogenes nasal colonization in nearly all cases.
Usual Adult Dose for Meningitis:
Caused by Streptococcus pneumoniae: 600 mg orally or IV once a day for 10 to 14 days, in patients with severe penicillin allergy needing empiric or specific coverage
Sometimes used as adjunctive therapy for penicillin-resistant (MIC greater than or equal to 2.0 mcg/mL) meningitis. Regimen consists of vancomycin IV and rifampin. In addition, rifampin is sometimes used as adjunctive therapy to vancomycin in patients with infected CSF shunts.
Usual Adult Dose for Leprosy -- Tuberculoid:
Paucibacillary (tuberculid or indeterminate): 600 mg orally once a month, plus dapsone 100 mg daily, for a total of 6 months of therapy
Usual Adult Dose for Leprosy -- Borderline:
Multibacillary (lepromatous or borderline): 600 mg orally once a month along with clofazimine, plus daily dapsone and clofazimine, for a total of 12 months of therapy
Usual Pediatric Dose for Meningococcal Meningitis Prophylaxis:
Treatment of asymptomatic carriers of Neisseria meningitidis to eliminate meningococci from the nasopharynx:
Less than 1 month: 5 mg/kg orally or IV every 12 hours for 2 days
1 month or older: 10 mg/kg (not to exceed 600 mg/dose) orally or IV every 12 hours for 2 days
Usual Pediatric Dose for Tuberculosis -- Active:
For pediatric patients, the manufacturer recommends: 10 to 20 mg/kg/day (not to exceed 600 mg/day) orally or IV
For patients less than 15 years, the ATS, CDC, IDSA, and American Academy of Pediatrics (AAP) recommend:
Daily regimen: 10 to 20 mg/kg/day (up to 600 mg/day) orally or IV
Intermittent regimen: 10 to 20 mg/kg (up to 600 mg/dose) orally or IV twice a week
For patients 15 years or older, the ATS, CDC, and IDSA recommend:
Daily regimen: 10 mg/kg (up to 600 mg/day) orally or IV once a day
Intermittent regimen: 10 mg/kg (up to 600 mg/dose) orally or IV 2 or 3 times a week
A three-drug regimen consisting of isoniazid, rifampin, and pyrazinamide is recommended in the initial phase of short-course therapy which is usually continued for 2 months. Treatment should then be continued with isoniazid and rifampin for at least 4 months. Treatment duration should be extended if the patient's sputum or culture remains positive, if resistant organisms are present, or if the patient is HIV positive.
The Advisory Council for the Elimination of Tuberculosis, the ATS, and the CDC recommend adding streptomycin or ethambutol as a fourth drug in a regimen including isoniazid, pyrazinamide, and rifampin for initial treatment of tuberculosis unless the probability of isoniazid or rifampin resistance is very low. The need for a fourth drug should be reevaluated when susceptibility test results are known. If current community rates of isoniazid resistance are less than 4%, initial treatment with less than 4 drugs may be considered.
Study (n=175)
Directly Observed Therapy (DOT) - Two weeks daily therapy:
Greater than 1 month:
Weeks 1 and 2: Daily dosing of rifampin 10 to 20 mg/kg/day, isoniazid 10 to 15 mg/kg/day, and pyrazinamide 20 to 40 mg/kg/day
Weeks 3 to 8: Twice weekly rifampin 10 to 20 mg/kg/dose, isoniazid 20 to 40 mg/kg/dose, and pyrazinamide 50 to 70 mg/kg/dose
Weeks 9 to 24: Twice weekly rifampin 10 to 20 mg/kg/dose and isoniazid 20 to 40 mg/kg/dose
Usual Pediatric Dose for Tuberculosis -- Latent:
Infants, children, and adolescents:
The ATS, CDC, and AAP recommend: 10 to 20 mg/kg/day (up to 600 mg/day) orally or IV for 4 to 6 months
Many drugs can interact with rifampin. Below is just a partial list. Tell your doctor if you are using:
acetaminophen (Tylenol);
a blood thinner such as warfarin (Coumadin);
a barbiturate such as phenobarbital (Solfoton);
diazepam (Valium) or similar medicines such as alprazolam (Xanax), chlordiazepoxide (Librium), midazolam (Versed), temazepam (Restoril), triazolam (Halcion), and others;
a beta-blocker such as atenolol (Tenormin), bisoprolol (Zebeta, Ziac), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), timolol (Blocadren), and others;
clofibrate (Atromid-S);
steroids such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others;
birth control pills or estrogen hormone replacement;
heart medicines such as digoxin (Lanoxin), disopyramide (Norpace), quinidine (Quinaglute, Quinidex), mexiletine (Mexitil), tocainide (Tonocard), verapamil (Calan, Verelan, Isoptin), or enalapril (Vasotec);
HIV medicines such as delavirdine (Rescriptor), saquinavir (Invirase, Fortovase), ritonavir (Norvir), nelfinavir (Viracept), and others;
ketoconazole (Nizoral), itraconazole (Sporanox), or fluconazole (Diflucan);
methadone (Dolophine);
phenytoin (Dilantin), ethotoin (Peganone), and mephenytoin (Mesantoin);
sulfa drugs (Bactrim, Gantanol, Septra, and others);
diabetes medication you take by mouth;
cyclosporine (Sandimmune, Neoral); or
theophylline (Elixophyllin, TheoCap, Theochron, Uniphyl).
See also: rifampin side effects (in more detail)
In the US, Gastromark (ferumoxsil systemic) is a member of the drug class magnetic resonance imaging contrast media.
US matches:
Ferumoxsil is reported as an ingredient of Gastromark in the following countries:
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Dominal forte may be available in the countries listed below.
Prothipendyl hydrochloride (a derivative of Prothipendyl) is reported as an ingredient of Dominal forte in the following countries:
International Drug Name Search
Dismolan may be available in the countries listed below.
Ondansetron is reported as an ingredient of Dismolan in the following countries:
Ondansetron hydrochloride (a derivative of Ondansetron) is reported as an ingredient of Dismolan in the following countries:
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Risperidon-ratiopharm may be available in the countries listed below.
Risperidone is reported as an ingredient of Risperidon-ratiopharm in the following countries:
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Ciplabutol may be available in the countries listed below.
Salbutamol sulfate (a derivative of Salbutamol) is reported as an ingredient of Ciplabutol in the following countries:
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